Abstract
Deep learning models often struggle to maintain generalizability in medical
imaging, particularly under domain-fracture scenarios where distribution shifts
arise from varying imaging techniques, acquisition protocols, patient
populations, demographics, and equipment. In practice, each hospital may need
to train distinct models - differing in learning task, width, and depth - to
match local data. For example, one hospital may use Euclidean architectures
such as MLPs and CNNs for tabular or grid-like image data, while another may
require non-Euclidean architectures such as graph neural networks (GNNs) for
irregular data like brain connectomes. How to train such heterogeneous models
coherently across datasets, while enhancing each model's generalizability,
remains an open problem. We propose unified learning, a new paradigm that
encodes each model into a graph representation, enabling unification in a
shared graph learning space. A GNN then guides optimization of these unified
models. By decoupling parameters of individual models and controlling them
through a unified GNN (uGNN), our method supports parameter sharing and
knowledge transfer across varying architectures (MLPs, CNNs, GNNs) and
distributions, improving generalizability. Evaluations on MorphoMNIST and two
MedMNIST benchmarks - PneumoniaMNIST and BreastMNIST - show that unified
learning boosts performance when models are trained on unique distributions and
tested on mixed ones, demonstrating strong robustness to unseen data with large
distribution shifts. Code and benchmarks: https://github.com/basiralab/uGNN
Abstract
Scientific progress is tightly coupled to the emergence of new research
tools. Today, machine learning (ML)-especially deep learning (DL)-has become a
transformative instrument for quantum science and technology. Owing to the
intrinsic complexity of quantum systems, DL enables efficient exploration of
large parameter spaces, extraction of patterns from experimental data, and
data-driven guidance for research directions. These capabilities already
support tasks such as refining quantum control protocols and accelerating the
discovery of materials with targeted quantum properties, making ML/DL literacy
an essential skill for the next generation of quantum scientists. At the same
time, DL's power brings risks: models can overfit noisy data, obscure causal
structure, and yield results with limited physical interpretability.
Recognizing these limitations and deploying mitigation strategies is crucial
for scientific rigor. These lecture notes provide a comprehensive,
graduate-level introduction to DL for quantum applications, combining
conceptual exposition with hands-on examples. Organized as a progressive
sequence, they aim to equip readers to decide when and how to apply DL
effectively, to understand its practical constraints, and to adapt AI methods
responsibly to problems across quantum physics, chemistry, and engineering.